Because Experience Matters
We are Siron Clinical, trusted industry experts in complex clinical trials across diverse therapeutic areas, including orphan disease, pediatric, and medical device sectors.
Our Services
Project Management
Flexibility, innovation, and integrity guide our approach to project management and leadership for the success of your clinical trials.
Clinical Monitoring
We provide passionate strategic knowledge, specific guidance, and expertise for study execution across multiple therapeutic areas.
Quality Assurance / Control
We pride ourselves on accuracy and integrity through a continual and dynamic process when it comes to quality assurance and quality control.
Regulatory Submissions
We manage the entire Regulatory Submission process carefully and efficiently, bringing the benefits of new treatments to patients sooner while maximizing research investments.
How is Clinical Trial Success Defined in Europe?
Bringing a product further down the development pipeline often requires conducting clinical research in Europe. However, navigating varied local regulations specific to each country, EMA, and cultural differences can be challenging. Download our RFI on to discover more about our insights, approach and experience.
Our Clients Say
VP Clinical Operations US, Oncology
'......to Regulatory agencies or ethics committees, the larger CROs had difficulty communicating prior learnings to internal teams and creating the same kinds of efficiency.'
VP Clinical Operations, Dermatology
'......in Europe, our partners for working there are critical to us. We need local partners whom we can truly rely on; whom we can absolutely trust. Siron is such a partner for us.'
VP, Clinical Operations US, Liver diseases
'......The Siron CRAs were an experienced and diligent part of our global team; we depended on them for their expertise and they did not disappoint.'
VP Clinical Operations US, Oncology
'......in getting studies approved in the EU, Siron Clinical played a vital role in us acquiring approval. Their management and oversight was a very positive experience for us.'
VP, Clinical Operations US, Liver diseases
'......a number of CRAs have remained at Siron for many years - there has been very little turnover in my experience. Again, this reflects Siron's excellent management and leadership.'
VP Clinical Operations, Dermatology:
'......have started quickly and smoothly, and all activities are timely and precise. The Siron team is very proactive, with a focus on solutions to any problem that might arise.'
News
How Regulation and Technology Impacted Clinical Research in 2023
This has been a year of change in the clinical trials landscape, with developments in regulation and the evolution of technology driving the move toward more patient...
Take a peek behind the scenes: how Siron Clinical works with clients
Choosing a partner to support your clinical trial is a big decision, and understanding what your collaboration might look like can help. After more than two decades of...
Five tips for keeping up-to-date with the latest in clinical trials
In the fast-moving field of clinical trials, it can be challenging to keep up-to-date with the latest news, views, and changes. But with new regulation frequently...
Preparation, quality and the local touch: Siron Clinical’s experience with the CTIS
Now nearing the end of their second year in use, the EU’s Clinical Trial Regulation and its associated Clinical Trials Information System (CTIS) have meant some big...
How small biotech can overcome clinical trial hurdles
Small biotech companies are responsible for a significant proportion of newly approved medicines, especially for rare diseases. But with limited resources, budget...
Quality assurance – why it's important and how to do it
Quality assurance is a critical element of a clinical trial, as it ensures the safety of the participants, as well as the reliability and integrity of the documentation...
Recruitment, decentralization and transparency: a round-up of the latest clinical trial news
With new regulations and guidance promoting transparency, growing calls for better representation, and accelerated developments in technology, the clinical trials...
Four factors to consider for your cardiovascular clinical trial
Cardiovascular clinical trials are essential in developing interventions like treatments and medical devices for a wide range of cardiovascular diseases. The sheer size...
Patient recruitment – how to get (and keep) participants
Finding and enrolling patients can be one of the most challenging aspects of setting up a trial – and even if you reach your recruitment goals, you face the task of...
What to do with negative results clinical research – and why they don’t equal failure
It can be disappointing if your trial generates negative results; you may feel it has been a waste of time and resources. But negative results do not necessarily mean...
Medical device clinical trials can be challenging – here’s what to expect
Medical devices are vital for diagnosing, treating and monitoring diseases, saving lives and keeping us alive. There are about 2 million medical devices on the market...
How an eTMF can improve your clinical trial
When you’re running a clinical trial, you need to make sure that your records, from protocols to results, are compliant, organized and managed so that they’re always...
Four clinical trial trends to watch in 2023
In 2022, the clinical trials industry adjusted to post-pandemic reality, embracing new innovations that emerged from COVID-19. We expect many of these to continue: here...
3 Tips for Running a Successful Oncology Trial
Cancer is a leading cause of death globally, but the more we understand about this complex group of diseases, the more opportunities we have to target it with new...
Why patients must remain central as clinical trial tech develops
The latest trends in clinical trials, like decentralization and AI, can help make a trial more efficient, effective and successful. But what if the patients at the...
Point-of-care clinical trials: the right approach for your research?
What if a clinical trial were integrated seamlessly into patient care, so each patient could get maximum benefit from the treatment on trial, while saving time and...
Pediatric Rare Disease Clinical Trials
There are many challenges to overcome if pediatric rare disease treatments are being tested, those challenges can be significantly greater....
How to train a clinical trial team (from a distance)
Before a clinical trial can start, everyone on the team needs to understand the research and their own role in it. Good training can support a successful result and...
Why representation is important in clinical trials
The clinical trials news has been dominated by studies showing underrepresentation in clinical trials, and experts calling for an end to it. But why is representation...
Meet Clinical Trial Manager Ingrid Meine
At Siron Clinical, people are our biggest strength. Here we meet Ingrid Meine, who joined the Siron Clinical team as Clinical Trial...
Five Ways Decentralization Can Help Your Trial Succeed
The pandemic accelerated innovation around clinical trial decentralization, but remote approaches are here to stay. Here are five ways decentralization can help you...
Site Initiation Visits: Starting Your Trial On Track
To get the best start with a clinical trial, we carry out a site initiation visit (SIV). In this post, we look at what that entails and how we ensure it sets the trial...
Modernizing Clinical Trials: Three Innovative Trial Designs From The FDA
There are many different types of clinical trial design, but most of the approaches we take to clinical research have been around for many years. Innovation in trial...
The EU’s move to better clinical trials that address patients’ needs – what you need to know
Clinical trials in the EU are changing in 2022 – the new EU Clinical Trials Regulation comes into force, backed by the Clinical Trials Information System (CTIS) and...
Clinical Trial Support – 5 Reasons Why You Don’t Have To Do Everything Yourself
Clinical trials are complex, which means they involve a lot of work and require a range of skills and experience. It can be daunting when you start planning a clinical...
120 Clinical Trials In 20 Years: Discover Siron Clinical’s Expertise
One of the key drivers of our success as a CRO is our extensive experience with clinical trials across phase I and II trials, and in therapeutic areas including...
How Clinical Trial Data Is Used – And Why It’s Important To Publish
How are the results of clinical trials applied? A clinical trial can generate a huge amount of data. Collecting, storing and managing that data is challenging,...
A Phase II Clinical Trial, Step By Step
Your drug has passed through the phase I clinical trial and you’ve selected and contacted the sites you want to work with. Now it’s time to get your trial up and...
FDA, IRB, EMA… What Role Do Agencies Play In Clinical Trials?
At first glance, it’s abbreviation soup – EMA, FDA, NIHR, OHRP, IRB – but this collection of organizations is responsible for making sure clinical trials are run...
What Is a CRO And How Can They Help You?
A clinical trial involves complex overlapping processes, many of which require specialized expertise and experience. So how can you run a clinical trial successfully if...
Clinical Trials Versus Clinical Studies: What’s The Difference?
As a CRO, we talk about clinical research and clinical trials, but what’s the difference? Can the two terms be used interchangeably? And why does it...
Behind The Scenes At Siron Clinical
When Jan Balemans, Founder and CEO of Siron Clinical, started the company in 2000, he was the first member of an expert team that would grow steadily over the next two...
COVID-19, Decentralization And Diversity: Roundup Of The Latest Clinical Trial News
At Siron Clinical, we keep up with the latest news and aim to share important updates on our social media channels. Here is a round-up of the hot topics being discussed...
Orphan Indications: Exploring Siron Clinical’s Specialized Therapeutic Expertise
According to the European Medicines Agency (EMA), about 30 million people in the EU suffer from a rare disease. Since Siron Clinical was founded over 20 years ago, we...
Clinical Monitoring: How The pandemic Has Helped Us Develop Remote Approaches
Clinical monitoring has been a challenge during the COVID-19 pandemic, but at Siron Clinical, we had the knowledge and experience to run with new remote...
5 Clinical Trial Whitepapers (and Other Things) You Should Read
There is a plethora of information available online about clinical trials, from the basics and fundamentals to glimpses of the future. When you’re overwhelmed by...
Why Run a Clinical Trial?
The clinical trial process is arduous, strict and highly regulated. This is a result of hundreds of years of improvement and evolution. It’s also the reason clinical...
Connect with Siron Clinical CEO Jan Balemans Online
Digital events are supporting connection during the pandemic. On 23-26 November 2020, Jan Balemans is attending Biotechgate Digital Partnering in his role as CEO of...
EU Regulations: A Guide For US Companies
We recently published a free eBook on EU regulations. Who says regulations can not be easy and clear? We share some of our insights from the eBook in the infographic...
A Roundup Of The Latest Clinical Trial News
With the time flying by so fast, it’s easy to miss clinical trial news. We’ve gathered some recent news stories to fill in the...
Did You Know? Five Facts from Siron Clinical’s New eBook
The eBook contains a wealth of information and practical tips to help you; here are five things you did not know about running a trial in the...
Starting a Clinical Trial in the EU: Siron Clinical Launches New eBook
There is great opportunity for US companies to run clinical trials in the EU, but it can be challenging to navigate the unfamiliar and complex approval processes. In a...
Celebrating 20 years of Siron Clinical
This month we celebrate a milestone for Siron Clinical: 20 years of success as a CRO. We couldn’t be prouder of our rich history, accolades and accomplishments that...
What will Clinical Trials Look Like After the pandemic? Three Predictions from Siron Clinical.
If you follow Siron Clinical on social media, you may have noticed that we have been sharing news, opinions and information about the Coronavirus pandemic in relation to...
How to Succeed with Clinical Trials in Europe
We recently published a downloadable RFI which details our extensive experience with clinical trials in Europe. read highlights from the RFI document in the...
What Spells Success for Clinical Trials in Europe?
Clinical trials are unique, each with their own protocol, parameters, participants and therapeutic areas. They can differ greatly, covering a range of treatment and...
After the Pandemic: How to Start Preparing Your Clinical Trials for What Comes Next
As the COVID-19 pandemic continues, day after day we are inundated with information. For the CRO industry, the message is that measures are in place and everything is...
Managing Your Clinical Trial During COVID-19: Siron Clinical Can Help You Navigate Through Uncertain Times
I would like to begin by saying I hope you and your family are staying safe and healthy during this uncertain time. I know the COVID-19 pandemic is having an impact,...
Siron Clinical Clients Benefit From Cutting-edge eTMF Thanks to New Partnership with Montrium
Clinical trials come with vast amounts of information, and a new partnership between Siron Clinical and Montrium will ensure clients benefit from efficient and effective...
Peanut Allergy Immunotherapy Acquires FDA Approval With Siron Clinical's Support
An estimated 1 in 50 children over the age of 4 are allergic to peanuts; a new immunotherapy now approved by the FDA, following phase III trials carried out with support...
Siron Clinical is attending BIO-Europe Spring 2020
BIO-Europe attracts a wide range of business leaders, including senior executives of leading biotech companies, business development teams from large and midsize...
From Siron to Siron Clinical – The Journey of Discovering Our Future
For the past 20 years, Siron Clinical has provided a high level of expertise in clinical trials for biotechs. Discover our Siron Clinical rebrand...
Siron Rebrands to Siron Clinical with a Renewed Focus on the Future
As we step into 2020, the team at Siron Clinical felt it was time to take our brand into the new decade. With 20 years of experience under our belts, we wanted to...
Siron Clinical Attends BioFit 2019
Siron Clinical will attend Biofit in Marseille on 10-11 December...
Siron Clinical Attends Clinical Trials Europe 2019
Siron will attend Clinical Trials Europe in Barcelona on 19-21 November...
Experience Matters
We offer unparalleled knowledge, support, guidance, and extremely experienced clinical research professionals to the biotechnology, life science, and medical device industries. We are committed to leading the development of new and advanced treatments.